LaFayette led 24-17 at halftime, but pulled away by outscoring the Eagles in the fourth quarter, 21-5.
Alex Kelehear hit five three-pointers and finished with 15 points. Bryson Giddy had eight points and 11 rebounds, while KaDarrin Ramsey went for eight points and 10 rebounds.
Marquie Davis had 16 points for Chattanooga Valley, while Markeion Jones and Micah Genter both had five points each.
Information on the girls' game was not available as of press time.